- Strategies to prevent surgical site infections should always include attention to
-infection control strategies
-surgical technique
-hospital and operating room environments
-instrument sterilization processes
-perioperative optimization of patient risk factors
-appropriate management of surgical wounds
- Antibiotic prophylaxis should be administered for operative procedures that have a high rate of postoperative wound infection, or when foreign materials is implanted.
- Antibiotic prophylaxis should be bactericidal, nontoxic, and inexpensive. Antibiotics should have in vitro activity against the common organisms that cause postoperative wound infection after a specific surgical procedure.
- Broad-spectrum antibiotics should be avoided always for surgical prophylaxis.
- Antibiotic prophylaxis should be administered not more than 30 to 60 minutes before surgery.
- Additional antibiotic doses should be administered intraoperatively for prolonged procedures.
- Prolonged postoperative AP should be always discouraged.